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Voice Abstract

Effect of Life Style Intervention on Risk Parameters in Young Indians Suffering Cad
(Short Communication)
  • 1 Department of Biostatistics and Epidemiology, Public Health College, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • 2 Department of Community Medicine, UCMS>B Hospital, University of Delhi, New Delhi, India
  • 3 Department of Medicine/Preventive Cardiology HIMSR&AHA, Centenary Hospital, Hamdard University, New Delhi, India
  • Correspondence should be addressed to Ali Dehghani, Department of Biostatistics and Epidemiology, Public Health College, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; Tel: ; Fax: ; Email:


Coronary artery disease (CAD) in young (age≤35-yrs) is increasing in the Indian subcontinent. It constitutes 11-14% of total CAD burden in this country. In the background of dual epidemic of communicable and non-communicable diseases prevailing in India, the crucial issue is can we prevent the risk of CAD in young by appropriate health intervention? We conducted a case-control interventional study in young CAD subjects and collected data from first episode CAD in patients (age≤35 yrs) admitted in coronary care unit of the GTB Hospital and studied the effect of life style intervention with the help of power point presentation and booklet on risk factor profile (smoking, hypertension, diabetes mellitus, dyslipidemia, obesity , sedentary life, dietary habit) and short term mortality at three and six months follow up in the experimental and control groups. 49 (9.8 %) subjects were young (≤35 35yrs). Majority of them were male (81.6%), belonging to low socioeconomic group (85.7%) and were smokers, (69.4%). We observed a significant reduction in smoking (p<0.008) and significant difference in decreasing total cholesterol [Median(IQR) from170(133-179) mg/dl to 131(87.25-171.5)mg/dl] p<(0.046) and fat intake [Median(IQR) from 56.35(41.95-78.35) g/day to 42.97(28.93-65.28) g/day ] (p<0.048) in study groups after six months follow up, whereas control group showed significance difference in the increase of total cholesterol [Median (IQR) from 159.5(118.75-197.5) mg/dl to 162(81.5-196.5) mg/dl ]( p< 0.038) and total fat [Median(IQR) from 53.56(31.28-79.01) to 63.5(47.41-71.01)] (p<0.028). During six months follow up one patient in study group who was both a smoker and an alcoholic died. The findings of this study revealed that by adopting lifestyle changes and food habit modification CAD, risk factors like as smoking, hypercholesteraemia and fat intake can be modified which may be beneficial for the individuals in preventive future episodes of acute coronary syndrome.


Lifestyle intervention, CAD, Young Indians

  • * This paper has been published in Volume 1, 2016, Issue 1, Pages: 20-23
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